<p>The role of nurses inpatient safety programs still requires special attention from hospital management.To<br />realize high quality and safety carebased on patient safety programs, nurses requires knowledge, skills, and<br />attitudes as well as a variety of competencies. The purpose of this research is to determine the relationship<br />of nurses’ knowledge and nurses’ attitudes as the implementation of patient safety at general inpatient<br />instalationinRSUD Jombang in 2013. The researcher uses research design of analytic correlation with crosssectional<br />approach. The number of population consists of 132 nurses workingat general inpatient instalationin<br />RSUD Jombang, and its sample consists of 99 nurses which are treated by using “proportionate random sampling<br />techniqueâ€. The independent variable in this research is the nurses' knowledge, while the dependent variable is<br />the nurses’ attitudes. The researcher uses data collection byusinginstruments such as questionnaires, where as<br />the data analysis using Chi Square. The results show that the knowledge of nurses about patient safety less<br />categorized by 51.5% and 48.5% considered good. As for the attitude of nurses on patient safety<br />implementation categorized by 53.5% positive and 46.5% negative categorized. Chi Square test of two<br />variables is obtained value Ï = 0.032 The conclusion of this researchindicates that there is a significant relationship<br />of nurses’ knowledge and nurses' attitudes in the implementation of patient safety atgeneral inpatient instalation<br />inRSUD Jombang 2013.</p><p><br />Keywords: knowledge, attitudes, patient, safety</p>