<p>Labor pain is a physiological condition that is generally experienced by almost all mothers giving birth during the 1st active phase. One non-pharmacological effort to reduce labor pain by giving acupressure at points BL67 (Zhiyin) and BL60 (Kunlun). The purpose of this study was to determine the differences in the effect of acupressure on BL67 (Zhiyin) and BL60 (Kunlun) point on the intensity of labor pain when 1 active phase. The design using was quasi Experiment with the approach Two Group Pre-Post Test Design using a purposive sampling technique. Population all mothers gave birth at PMB clinic midwife Siti Rofi’atun Sambirejo Jogoroto as many as 20 respondents (treatment group acupressure BL67 n=10, BL60 n=10) that fulfilled the inclusion and exclusion criteria. The research instrument used a numeric rating scale (NRS), the data were analysed using paired sample T-test and Independent T-test samples with α≤ 0,05. The results showed that there was an effect ofacupressure therapy BL67(Zhiyin) and BL60(Kunlun) on the intensity of labor pain at 1 active phase with a sig value p&lt;0,05. There were no significant differences in the two groups (5,60 ± 8,43 vs 5,90 ± 1,853; p≥ 0,05. Acupressure at points BL67 (Zhiyin) and BL60 (Kunlun) are both effective in reducing the intensity of labor pain and can be used as an alternative to reduce labor pain.</p>